After Vinyl is bit by a radioactive spider, the once carefree girl now needs to learn some responsibility as Spider-Woman. Learning to help the city and her loved ones against those who want to hurt them.
Doctor Whooves and his friends have barely escaped Tirek's grasp, only to find themselves in Golden Oaks Library moments before it is destroyed. Turns out the library was hiding secrets of its own and sent them back in time for an unknown purpose...
Berry Punch leads a great life. But her daughter's sire suddenly takes an interest after never before seeing the filly. Berry knows he must have an ulterior motive, so she plans to confront him and, if necessary, make sure the past stays the past.
After a deadly cutie pox outbreak devastates Equestria, Princess Celestia activates the Strategic Homeland Division. As a Division Agent, Shining Armor must fight to take back the city of Manehattan and discover the origins of the deadly outbreak.