(Set 6 years after the FMA Magna's end, this will be following the magna continuity)
Alchemy, the science of understanding a substance, breaking it down, and restructing it into a new form.
Twilight Sparkle, a mage, must now figure out how to handle this science as she is thrown into a different world after saving her trusted assistant. Her magic gone, she learns from an experienced Alchemist as she goes off in search of the only stone that can bring her home.